Research
Cannabinoid Research
There is growing research that has shown cannabidiol (CBD) found in cannabis hemp may be therapeutic for many conditions. Below is a list of reports compiled primarily from PubMed, an online service of the U.S. National Library of Medicine, as well as articles and stories from other publications. Other cannabinoids are occasionally mentioned in the articles below for their therapeutic potential- THC, CBDa (cannabidiol in its raw acid form), THCV, CBG, and CBDV, for example.
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Links are organized by condition alphabetically.
General
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CBD: From an inactive cannabinoid to a drug with wide spectrum of action
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CBD as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress
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CBD: An overview of some chemical and pharmacological aspects
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The endocannabinoid system as an emerging target of pharmacotherapy
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Targeting the endocannabinoid system with cannabinoid receptor agonists
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Emerging strategies for exploiting cannabinoid receptor agonists as medicines
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Understanding the molecular aspects of THC and CBD as antioxidants
Acne
Alzheimer's disease
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Cannabinoids for the Treatment of Agitation and Aggression in Alzheimer’s Disease
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The therapeutic potential of the endocannabinoid system for Alzheimer’s disease
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A molecular link between the active component of marijuana and Alzheimer’s disease pathology
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Neuroprotective effect of CBD... on beta-amyloid-induced toxicity in PC12 cells
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The Potential Therapeutic Effects of THC on Alzheimer’s Disease
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The role of the endocannabinoid system in Alzheimer’s disease
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The role of phytochemicals in the treatment and prevention of dementia
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Cannabinoids for treatment of Alzheimer’s disease: moving toward the clinic
Antibacterial resistance
anxiety
Arthritis
Autism
Cancer Pain
Colitis and Crohn's Disease
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CBD reduces intestinal inflammation through the control of neuroimmune axis
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Topical and systemic cannabidiol improves trinitrobenzene sulfonic acid colitis in mice
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Cannabinoids and the gut: New developments and emerging concepts
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Cannabinoids and gastrointestinal motility: Animal and human studies
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Hergenrather presents study of Crohn’s patients as a template for clinical research on Cannabis
Coronavirus (COVID-19/SARS-CoV-2)
Depression
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Endocannabinoid system dysfunction in mood and related disorders
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The endocannabinoid system and the treatment of mood and anxiety disorders
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Endocannabinoid signaling in the etiology and treatment of major depressive illness
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Antidepressant-like effects of cannabidiol in mice: Possible involvement of 5-HT1A receptors
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Serum contents of endocannabinoids are correlated with blood pressure in depressed women
Epilepsy and Seizures
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Report of a parent survey of CBD-enriched cannabis use in pediatric treatment-resistant epilepsy
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Medicinal marijuana stops seizures, brings hope to a little girl
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Cannabis, CBD, and epilepsy – From receptors to clinical response
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Chronic administration of CBD to healthy volunteers and epileptic patients
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Endocannabinoid system protects against cryptogenic seizures
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Cannabidiol: Pharmacology and potential therapeutic role in epilepsy and other neuropsychiatric disorders
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From the Editors: Cannabidiol and medical marijuana for the treatment of the treatment of epilepsy
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CBD exerts anti-convulsant effects in animal models of temporal lobe and partial seizures
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Cannabidiol displays antiepileptiform and antiseizure properties in vitro and in vivo
Fibromyalgia
Inflammation
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The endocannabinoid system: an emerging key player in inflammation
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Anti-inflammatory role of cannabidiol and O-1602 in cerulein-induced acute pancreatitis in mice
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Cannabinoids, endocannabinoids, and related analogs in inflammation
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
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Cannabidiol reduces intestinal inflammation through the control of neuroimmune axis
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Diabetic retinopathy: Role of inflammation and potential therapies for anti-inflammation
Irritable bowl syndrome
Migraine
Mood Disorders
Multiple Sclerosis (MS)
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Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
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Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
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Sativex long-term use: An open-label trial in patients with spasticity due to multiple sclerosis
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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
Nausea
Neuropathic Pain
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Meta-analysis of cannabis based treatments for neuropathic and multiple sclerosis-related pain
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Sativex successfully treats neuropathic pain characterised by allodynia: clinical trial
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Neuropathic orofacial pain: Cannabinoids as a therapeutic avenue
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Oromucosal delta9-THC/CBD for neuropathic pain associated with multiple sclerosis
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Antihyperalgesic effect of a Cannabis sativa extract in a rat model of neuropathic pain
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Cannabinoids suppress inflammatory and neuropathic pain by targeting α3 glycine receptors
Osteroperosis/ Bone Health
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CBD Enhances Fracture Healing and Stimulates Lysyl Hydroxylase Activity in Osteoblasts
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Cannabinoid receptors as target for treatment of osteoporosis: A tale of two therapies
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Cannabinoids and the skeleton: From marijuana to reversal of bone loss
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The endovanilloid/endocannabinoid system: A new potential target for osteoporosis therapy
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Regulation of bone mass, bone loss and osteoclast activity by cannabinoid receptors
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Long-chain polyunsaturated fatty acids may mutually benefit both obesity and osteoporosis
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Skeletal lipidomics: Regulation of bone metabolism by fatty acid amide family
PTSD
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The endocannabinoid system provides an avenue for evidence-based treatment development for PTSD
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Enhancing cannabinoid neurotransmission augments the extinction of conditioned fear
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Modulation of Fear Memory by Dietary Polyunsaturated Fatty Acids via Cannabinoid Receptors
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Non-antidepressant long-term treatment in post-traumatic stress disorder
Rheumatism
Skin Conditions
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CBD exerts sebostatic and antiinflammatory effects on human sebocytes
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The endocannabinoid system of the skin in health and disease
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Epigenetic control of skin differentiation genes by phytocannabinoids
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Attenuation of allergic contact dermatitis through the endocannabinoid system
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Topical cannabinoid agonists. An effective new possibility for treating chronic pruritus